Cooperative Research Centres

Establishing the prevalence of HPV infection in Indigenous and non-Indigenous women in Australia, urban and rural: WHINURs - Women's - HPV - Indigenous - Non-Indigenous - Urban - Rural - Study

CRCAH Project No: CD106 

Administering Organisation:
Menzies School of Health Research

Project Leader:
Professor Suzanne Garland
Royal Women's Hospital, Melbourne

Contact Details:
Suzanne.Garland@rch.org.au

Program Manager:
Arwen Pratt,
Chronic Conditions program

Partners Involved:

  • Royal Women’s Hospital Melbourne, VIC

  • Menzies School of Health Research, NT

  • Danila Dilba Aboriginal Medical Services, NT

  • NT Department of Health and Community Services

  • National Centre for Immunisation Research and Surveillance, The University of Sydney and The Children’s Hospital at Westmead, NSW

  • Division of Microbiology and Infectious Diseases, PathCentre (The Western Australian Centre for Pathology & Medical Research), WA

  • Kimberley Population Health Unit, Kimberley Health Region, Broome, WA

  • Townsville Aboriginal and Islanders Health Services (TAIHS), QLD

  • Aboriginal Medical Services in Victoria, NSW, Western Australia and the Northern Territory

  • CRCAH
Project summary:

The human papillomavirus (HPV) is the most common viral sexually transmitted infection. The formulation of appropriate recommendations for use of prophylactic HPV vaccines in Australia requires data on the pattern of HPV infection by age and Indigenous status and which is generalisable at the population level. This will be useful pre-vaccine rollout to ultimately measure the vaccine effectiveness, including the use of disease modelling to estimate likely vaccine impacts.

The pilot study focused on two communities, one remote Indigenous community and one urban Indigenous community, to test and refine information, training materials and data collection processes in consultation with primary health care staff and community members. Preliminary work was required to undertake further consultations with Aboriginal Medical Services and other Indigenous health organizations, to develop information materials to inform Indigenous women about HPV infection and the proposed research study, and to develop clinical guidelines for health care providers and for women who are found to have an HPV infection with a cancer-causing genotype.

There were several funding bodies (including the CRCAH) for this study to support the development of information materials and to support the Indigenous steering committee. The pilot study was the first-stage of a wider project that has sites in Queensland, Victoria, Western Australia, Northern Territory, New South Wales and Tasmania.

 

Summary of projected outcomes:

Results of this pilot study were used in modeling of the vaccination impact of HPV vaccines in the Australian population. Information obtained was useful in estimating the likely impact of vaccination against HPV infection in Australia, especially those at high risk of cervical cancer (ICC). In the longer term, the study will provide essential baseline information on types of HPV affecting Australian women over time, important in evaluating the impact of a vaccination program.

 

Timelines:

This pilot study for the project was carried out from 2004 to 2007.

 

Project Publications:

A final report is currently in development and will be available in 2008.


Related Links:

Investigating cross-cultural responses to the introduction of the Human papillomavirus [HPV] vaccine (Margaret Heffernan, Student)

 

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[Page last updated 11 July 2008]

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